XMAP
June 16, 2011 :: Posted by - maureen :: Category - Bio Technology
xMAP® is commonly called as “Bead Array Technology”. It is a novel concept developed to eliminate the limitations of planar microarrays during array preparation. Planar microarrays employs glass slides as solid substrate which makes it technically challenging and laborious. With the advent of this new high throughput platform, there is a gradual shift from the microarray format of glass slides to the efficacious bead format. Being more flexible in array preparation the bead format is easy to use, cost effective and offers faster hybridization solution kinetics along with statistical superiority as compared to the conventional technique. In other assay chemistries utilizing a solid phase, the reaction kinetics can be adversely affected by immobilization of a reactant on a solid surface. The effects are less severe for a microsphere in suspension than for a flat array as the diffusion rate of the immobilized capture probe can be slower and the effective concentration is reduced as compared to free DNA in solution
In broader terms the integration of three prominent technologies: PCR, microarray and fluorimeter into a small bead makes xMAP® both sensitive and specific.
xMAP® or the suspension array .. more» 


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